EUSynBioSeminars

Since May 2020, we have been hosting this online seminar series, where we invite researchers from the synthetic biology community to give short presentations about their most recent work. The aim is to offer a platform for a wide range of topics related to synthetic biology, accessible to everyone for free.

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Upcoming Seminars


Selective RNA pseudouridinylation using circular gRNA in designer organelles
Nov
21

Selective RNA pseudouridinylation using circular gRNA in designer organelles

Thursday, 21 November 2024

Join the next #EUSynbioSeminar and hear Lukas Schartel from the International Max Planck Research School (IMPRS) of Cellular Biophysics give a talk titled "Selective RNA pseudouridinylation using circular gRNA in designer organelles."

RNA modifications play a pivotal role in the regulation of RNA chemistry within cells. Several technologies have been developed with the goal of using RNA modifications to regulate cellular biochemistry selectively, but achieving selective and precise modifications remains a challenge. Using designer organelles, we can modify mRNA with pseudouridine in a highly selective and guide-RNA-dependent manner. These designer organelles are based on the principle of phase separation, a central tenet in developing artificial membraneless organelles in living mammalian cells. In addition, we used circular guide RNAs to markedly enhance the effectiveness of targeted pseudouridinylation. Our studies offer spatial engineering by means of optimized RNA editing organelles (OREO) as a complementary tool in using targeted RNA modification to expand potential avenues for future investigation.

Register here to join us the 21st of November at 16:00 CET

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Engineering Promoters and 5' UTRs: A Journey from Random DNA to Rational and Predictable Design with Transformer Models
May
30

Engineering Promoters and 5' UTRs: A Journey from Random DNA to Rational and Predictable Design with Transformer Models

Thursday, 30 May 2024

Join the next #EUSynBioSeminar and hear Dr. Rahmi Lale from the Norwegian University of Science and Technology (NTNU) and co-founder and CEO of Syngens give a talk titled "Engineering Promoters and 5' UTRs: A Journey from Random DNA to Rational and Predictable Design with Transformer Models"

Register here to join us the 30th of May at 16:00 CET

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EUSynBioSeminar: “Biosaftey in Synthetic Biology: A Genetic Firewall Metric”
Jan
19

EUSynBioSeminar: “Biosaftey in Synthetic Biology: A Genetic Firewall Metric”

EUSynBioS seminars are back! Our first speaker of 2023 is CEO/Founder of BioFacation, Dr. Markus Schmidt.

Dr. Markus Schmidt has an interdisciplinary background in biomedical engineering, biology and technology assessment. He initiates and executes a number of projects dealing with responsible research and innovation in emerging science and technology areas, bringing together various stakeholders from science, regulation, industry, civil society and art. Markus’s talk is entitled ‘Biosaftey in synthetic biology: a genetic firewall metric’.

Register here and join us on January 19th at 16:00 CET

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Past seminars

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